Rice Oligopeptide-91 SH-Polypeptide-1

INCI: RICE OLIGOPEPTIDE-91 SH-POLYPEPTIDE-1

CAS Number
Not assigned (synthetic/recombinant peptide complex) [^1_13]
Function
Humectant, skin conditioning (anti-aging peptide complex) [^1_13][^1_14]
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes General cosmetic ingredient; not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

SH-Polypeptide-1 is synthetic human polypeptide-1 (related to growth hormone sequence). Verify regulatory acceptance in target markets โ€” some jurisdictions may classify growth-factor-like peptides differently. No CIR or SCCS safety opinion published. Origin noted as "plant synthetic" [^1_13]. Obtain full manufacturer dossier including sequence verification, endotoxin testing, and stability data

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Rice Oligopeptide-91 SH-Polypeptide-1 safe in cosmetics?

SH-Polypeptide-1 is synthetic human polypeptide-1 (related to growth hormone sequence). Verify regulatory acceptance in target markets โ€” some jurisdictions may classify growth-factor-like peptides differently. No CIR or SCCS safety opinion published. Origin noted as "plant synthetic" [^1_13]. Obtain full manufacturer dossier including sequence verification, endotoxin testing, and stability data The EU classifies Rice Oligopeptide-91 SH-Polypeptide-1 as "permitted". Safety rating: MODERATE.

Is Rice Oligopeptide-91 SH-Polypeptide-1 allowed in the EU?

Rice Oligopeptide-91 SH-Polypeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice Oligopeptide-91 SH-Polypeptide-1 do in cosmetics?

Rice Oligopeptide-91 SH-Polypeptide-1 functions as: Humectant, skin conditioning (anti-aging peptide complex) [^1_13][^1_14]. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (synthetic/recombinant peptide complex) [^1_13].

What is the Margin of Safety for Rice Oligopeptide-91 SH-Polypeptide-1?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Rice Oligopeptide-91 SH-Polypeptide-1 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Rice Oligopeptide-91 SH-Polypeptide-1 in your formulation.