Rice SH-Oligopeptide-1

INCI: RICE SH-OLIGOPEPTIDE-1

CAS Number
Not specifically assigned for rice variant (EGF analog)
Function
Skin Conditioning — EGF (Epidermal Growth Factor) analog promoting skin regeneration [^1_7][^1_8]
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

As an EGF mimic, theoretical concern about stimulating cell proliferation on damaged or compromised skin; should not be used on broken skin; strengthens barrier function and collagen production at cosmetic-level concentrations [^1_7][^1_8]

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Concern Level: Moderate

Frequently Asked Questions

Is Rice SH-Oligopeptide-1 safe in cosmetics?

As an EGF mimic, theoretical concern about stimulating cell proliferation on damaged or compromised skin; should not be used on broken skin; strengthens barrier function and collagen production at cosmetic-level concentrations [^1_7][^1_8] The EU classifies Rice SH-Oligopeptide-1 as "permitted". Safety rating: MODERATE.

Is Rice SH-Oligopeptide-1 allowed in the EU?

Rice SH-Oligopeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice SH-Oligopeptide-1 do in cosmetics?

Rice SH-Oligopeptide-1 functions as: Skin Conditioning — EGF (Epidermal Growth Factor) analog promoting skin regeneration [^1_7][^1_8]. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for rice variant (EGF analog).

What is the Margin of Safety for Rice SH-Oligopeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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