Moderate Cosmetic Ingredient

Rice SH-Polypeptide-1

INCI: RICE SH-POLYPEPTIDE-1

CAS Number
Not specifically assigned for rice variant; parent sh-Polypeptide-1 = bFGF analog
Function
Skin Conditioning, Hair Conditioning — bFGF (basic Fibroblast Growth Factor) analog [^1_11]
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Promotes collagen, elastin, and hyaluronic acid synthesis; interacts with EGF and IGF-1 pathways; theoretical angiogenic activity (promotes blood vessel development) — avoid on vascular lesions or compromised skin [^1_11]

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Rice SH-Polypeptide-1 safe in cosmetics?

Promotes collagen, elastin, and hyaluronic acid synthesis; interacts with EGF and IGF-1 pathways; theoretical angiogenic activity (promotes blood vessel development) — avoid on vascular lesions or compromised skin [^1_11] The EU classifies Rice SH-Polypeptide-1 as "permitted". Safety rating: MODERATE.

Is Rice SH-Polypeptide-1 allowed in the EU?

Rice SH-Polypeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice SH-Polypeptide-1 do in cosmetics?

Rice SH-Polypeptide-1 functions as: Skin Conditioning, Hair Conditioning — bFGF (basic Fibroblast Growth Factor) analog [^1_11]. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for rice variant; parent sh-Polypeptide-1 = bFGF analog.

What is the Margin of Safety for Rice SH-Polypeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Rice SH-Polypeptide-1 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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