Saccharomyces/Phellodendron Amurense Bark Ferment Extract

INCI: SACCHAROMYCES/PHELLODENDRON AMURENSE BARK FERMENT EXTRACT

CAS Number
Not specifically assigned for fermented form (raw bark CAS: 164288-48-4 may apply to source)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; Phellodendron bark (Huang Bai) widely used in TCM-inspired cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Key concern: Berberine is a bioactive alkaloid with documented pharmacological activity โ€” verify residual berberine content post-fermentation; potential photosensitizer; may have drug-cosmetic interaction concerns in some jurisdictions; check if residual berberine levels exceed cosmetic-appropriate thresholds

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Saccharomyces/Phellodendron Amurense Bark Ferment Extract safe in cosmetics?

Key concern: Berberine is a bioactive alkaloid with documented pharmacological activity โ€” verify residual berberine content post-fermentation; potential photosensitizer; may have drug-cosmetic interaction concerns in some jurisdictions; check if residual berberine levels exceed cosmetic-appropriate thresholds The EU classifies Saccharomyces/Phellodendron Amurense Bark Ferment Extract as "permitted". Safety rating: MODERATE.

Is Saccharomyces/Phellodendron Amurense Bark Ferment Extract allowed in the EU?

Saccharomyces/Phellodendron Amurense Bark Ferment Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Saccharomyces/Phellodendron Amurense Bark Ferment Extract do in cosmetics?

Saccharomyces/Phellodendron Amurense Bark Ferment Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for fermented form (raw bark CAS: 164288-48-4 may apply to source).

What is the Margin of Safety for Saccharomyces/Phellodendron Amurense Bark Ferment Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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