Salacia Oblonga Root Extract

INCI: SALACIA OBLONGA ROOT EXTRACT

CAS Number
Not specifically assigned for cosmetic use (no CAS in CosIng)
Function
Skin conditioning; antioxidant activity demonstrated in vitro
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically regulated as cosmetic; used primarily in dietary supplements; no FDA cosmetic monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Root extracts show antiproliferative activity against cancer cell lines (IC₅₀ 44 μg/mL) — raises questions about cytotoxicity at cosmetic-relevant concentrations; contains anti-inflammatory phytochemicals that may modulate immune response; no CIR review; recommend patch testing and cytotoxicity assessment for topical use

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Salacia Oblonga Root Extract safe in cosmetics?

Root extracts show antiproliferative activity against cancer cell lines (IC₅₀ 44 μg/mL) — raises questions about cytotoxicity at cosmetic-relevant concentrations; contains anti-inflammatory phytochemicals that may modulate immune response; no CIR review; recommend patch testing and cytotoxicity assessment for topical use The EU classifies Salacia Oblonga Root Extract as "permitted". Safety rating: MODERATE.

Is Salacia Oblonga Root Extract allowed in the EU?

Salacia Oblonga Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Salacia Oblonga Root Extract do in cosmetics?

Salacia Oblonga Root Extract functions as: Skin conditioning; antioxidant activity demonstrated in vitro. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned for cosmetic use (no CAS in CosIng).

What is the Margin of Safety for Salacia Oblonga Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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