Sassafras Officinale Bark Extract

INCI: SASSAFRAS OFFICINALE BARK EXTRACT

CAS Number
84787-72-4 [^1_4]
Function
Skin Conditioning [^1_5]
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Safrole banned per 21 CFR 189.180; only safrole-free extracts may be used [^1_7][^1_8]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safrole is carcinogenic, mutagenic, hepatotoxic; sassafras oil is a narcotic precursor (EU Regulation 3677/90); Norwegian authorities recommend full prohibition of sassafras extracts in cosmetics even if "safrole-free" [^1_6]

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Sassafras Officinale Bark Extract safe in cosmetics?

Safrole is carcinogenic, mutagenic, hepatotoxic; sassafras oil is a narcotic precursor (EU Regulation 3677/90); Norwegian authorities recommend full prohibition of sassafras extracts in cosmetics even if "safrole-free" [^1_6] The EU classifies Sassafras Officinale Bark Extract as "permitted". Safety rating: POOR.

Is Sassafras Officinale Bark Extract allowed in the EU?

Sassafras Officinale Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sassafras Officinale Bark Extract do in cosmetics?

Sassafras Officinale Bark Extract functions as: Skin Conditioning [^1_5]. It is classified as a cosmetic ingredient in our database. CAS number: 84787-72-4 [^1_4].

What is the Margin of Safety for Sassafras Officinale Bark Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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