Saussurea Lappa Root Extract

INCI: SAUSSUREA LAPPA ROOT EXTRACT [^1_16][^1_18]

CAS Number
90106-55-1 [^1_16][^1_17]
Function
Skin conditioning [^1_17][^1_18]
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific monograph; permitted under general provisions; recognized in traditional medicine (Ayurveda) [^1_19]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

MAJOR FLAG: Costunolide and dehydrocostuslactone are strong haptens causing ACD [^1_3]; sesquiterpene lactones show cytotoxicity (CD₅₀ 1.6–3.5 µg/mL) [^1_4]; IFRA restricts costus root oil; must specify and control sesquiterpene lactone content; not recommended for leave-on products without comprehensive allergen risk assessment; *Saussurea costus* is also CITES Appendix I — most restrictive category, commercial trade essentially prohibited for wild specimens [^1_16][^1_4][^1_20]

⚠️
Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Saussurea Lappa Root Extract safe in cosmetics?

MAJOR FLAG: Costunolide and dehydrocostuslactone are strong haptens causing ACD [^1_3]; sesquiterpene lactones show cytotoxicity (CD₅₀ 1.6–3.5 µg/mL) [^1_4]; IFRA restricts costus root oil; must specify and control sesquiterpene lactone content; not recommended for leave-on products without comprehensive allergen risk assessment; *Saussurea costus* is also CITES Appendix I — most restrictive category, commercial trade essentially prohibited for wild specimens [^1_16][^1_4][^1_20] The EU classifies Saussurea Lappa Root Extract as "permitted". Safety rating: MODERATE.

Is Saussurea Lappa Root Extract allowed in the EU?

Saussurea Lappa Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Saussurea Lappa Root Extract do in cosmetics?

Saussurea Lappa Root Extract functions as: Skin conditioning [^1_17][^1_18]. It is classified as a cosmetic ingredient in our database. CAS number: 90106-55-1 [^1_16][^1_17].

What is the Margin of Safety for Saussurea Lappa Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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