Schisandrin

INCI: SCHISANDRIN (ALSO KNOWN AS SCHISANDROL A)

CAS Number
7432-28-2
Function
Antioxidant, skin conditioning (lignan compound from *Schisandra chinensis*)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; falls under general cosmetic ingredient provisions (no FDA pre-market approval required)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pure isolate โ€” ensure sourcing purity; no CIR safety assessment published; primarily studied as pharmaceutical active, not as cosmetic ingredient per se

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Concern Level: Low

Frequently Asked Questions

Is Schisandrin safe in cosmetics?

Pure isolate โ€” ensure sourcing purity; no CIR safety assessment published; primarily studied as pharmaceutical active, not as cosmetic ingredient per se The EU classifies Schisandrin as "restricted". Safety rating: GOOD.

Is Schisandrin allowed in the EU?

Schisandrin EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Schisandrin do in cosmetics?

Schisandrin functions as: Antioxidant, skin conditioning (lignan compound from *Schisandra chinensis*). It is classified as a cosmetic ingredient in our database. CAS number: 7432-28-2.

What is the Margin of Safety for Schisandrin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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