Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Major allergen: causes type IV delayed hypersensitivity reactions and occupational contact dermatitis; present in Arnica, Chamomile, Feverfew, and Asteraceae extracts; formulators should verify sesquiterpene lactone content and minimize levels.
Regulatory Flags
Frequently Asked Questions
Is Sesquiterpene Lactones safe in cosmetics?
Major allergen: causes type IV delayed hypersensitivity reactions and occupational contact dermatitis; present in Arnica, Chamomile, Feverfew, and Asteraceae extracts; formulators should verify sesquiterpene lactone content and minimize levels. The EU classifies Sesquiterpene Lactones as "permitted". Safety rating: POOR.
Is Sesquiterpene Lactones allowed in the EU?
Sesquiterpene Lactones EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sesquiterpene Lactones do in cosmetics?
Sesquiterpene Lactones functions as: Allergen/impurity constituent class; not assigned standard cosmetic function. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS — this is a structural class (e.g., alantolactone CAS 546-43-0; parthenolide CAS 20554-84-1).
What is the Margin of Safety for Sesquiterpene Lactones?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Sesquiterpene Lactones compliance across multiple jurisdictions:
Related Ingredients
Is Sesquiterpene Lactones in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sesquiterpene Lactones in your formulation.