SH-Oligopeptide-73

INCI: SH-OLIGOPEPTIDE-73

CAS Number
Not publicly assigned / not listed in CosIng with a CAS
Function
Skin Conditioning – Emollient; Skin Protecting
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes No specific FDA monograph; falls under general cosmetic ingredient regulation (no pre-market approval required under MoCRA). Not on FDA prohibited/restricted list

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

⚠ Limited independent safety data; synthetic analogue of Substance P neuropeptide — theoretically could modulate neurogenic inflammation at high concentrations

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is SH-Oligopeptide-73 safe in cosmetics?

⚠ Limited independent safety data; synthetic analogue of Substance P neuropeptide — theoretically could modulate neurogenic inflammation at high concentrations The EU classifies SH-Oligopeptide-73 as "restricted". Safety rating: MODERATE.

Is SH-Oligopeptide-73 allowed in the EU?

SH-Oligopeptide-73 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-Oligopeptide-73 do in cosmetics?

SH-Oligopeptide-73 functions as: Skin Conditioning – Emollient; Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned / not listed in CosIng with a CAS.

What is the Margin of Safety for SH-Oligopeptide-73?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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