Is SH-Pentapeptide-19 safe in cosmetics?
SH-Pentapeptide-19 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
SH-Pentapeptide-19
INCI: SH-PENTAPEPTIDE-19
SH-Pentapeptide-19 (CAS Not publicly assigned (listed without CAS in CosIng)) is a cosmetic cosmetic ingredient functioning as Skin conditioning; Enkephalin-mimetic peptide — mimics botulinum toxin effects. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly assigned (listed without CAS in CosIng)
View industrial chemical safety profile →
Function
Skin conditioning; Enkephalin-mimetic peptide — mimics botulinum toxin effects by relaxing facial muscles; anti-wrinkle
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA monograph; MoCRA self-assessment applies
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for SH-Pentapeptide-19.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for SH-Pentapeptide-19.
Frequently Asked Questions
Is SH-Pentapeptide-19 allowed in the EU?
SH-Pentapeptide-19 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does SH-Pentapeptide-19 do in cosmetics?
SH-Pentapeptide-19 functions as: Skin conditioning; Enkephalin-mimetic peptide — mimics botulinum toxin effects by relaxing facial muscles; anti-wrinkle. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (listed without CAS in CosIng).
Compliance Tools
Check SH-Pentapeptide-19 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is SH-Pentapeptide-19 in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for SH-Pentapeptide-19 in your formulation.