NOAEL Studies Cosmetic Ingredient

Silver Nitrate NOAEL Studies

INCI: SILVER NITRATE

CAS: 7761-88-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
NTP_ICE_eye_irritation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_eye_irritation GHS Classification 1 unitless Rabbit Ocular - In Vivo; Draize Eye Irritation/Corrosion Test sheet=Data; excel_row=1081; Record_ID=eye_irritation_119; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=GHS Classification; Response=1; Response_Unit=Unitless; Species=Rabbit; Reference=ICCVAM 2006; URL=https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation 9 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_skin_irritation Viability (240 minutes) 14.5 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2610; Record_ID=skin_irritation_invitro_2307; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=14.5; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (240 minutes) 1.2 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2611; Record_ID=skin_irritation_invitro_2309; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=1.2; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (240 minutes) 6.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2612; Record_ID=skin_irritation_invitro_2311; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (240 minutes); Response=6.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (3 minutes) 66.9 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2605; Record_ID=skin_irritation_invitro_2311; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=66.90; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (3 minutes) 12.1 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2608; Record_ID=skin_irritation_invitro_2307; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=12.1; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (3 minutes) 80.6 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2609; Record_ID=skin_irritation_invitro_2309; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (3 minutes); Response=80.60; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (60 minutes) 4.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2602; Record_ID=skin_irritation_invitro_2309; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=4.40; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (60 minutes) 13.4 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2604; Record_ID=skin_irritation_invitro_2307; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=13.4; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
NTP_ICE_skin_irritation Viability (60 minutes) 2.5 % - Dermal - In Vitro; EpiSkin Corrosion sheet=Data_invitro; excel_row=2613; Record_ID=skin_irritation_invitro_2311; Data_Type=In Vitro; Mixture=Chemical; DTXSID=DTXSID3032042; Assay=EpiSkin Corrosion; Endpoint=Viability (60 minutes); Response=2.5; Response_Unit=%; Reference=Alepee et al. 2014; 24211528; 10.1016/j.tiv.2013.10.016; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3032042
ToxValDB_ECOTOX 12 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECOTOX LOEC =6.47 mg/org-day Rat oral subchronic; 32 days subchronic LONG_REF=Folia Biol. (Prague)26(1): 47-52 Pribyl,T., V. Schreiber, and J. Jahodova Inhibition of Rat Serum Polyphenoloxidase Activity by Silver Ions Abolished by Administration of Copper Ions 1980; TITLE=Inhibition of Rat Serum Polyphenoloxidase Activity by Silver Ions Abolished by Administration of Copper Ions; AUTHOR=Pribyl,T., V. Schreiber, and J. Jahodova; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=69099; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1980; ORIGINAL_YEAR=1980; TOXICOLOGICAL_EFFECT=Enzyme(s): Ceruloplasmin activity; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity; STUDY_GROUP=ECOTOX:15599619:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=1f8be58eadbe8db6bf5ad6fe93d7f02e
ToxValDB_ECOTOX LOEL =5 mg/kg bw/day Rat injection acute; 1 days acute LONG_REF=Arch. Toxicol.74(4/5): 190-195 Sugawara,N., and C. Sugawara Competition Between Copper and Silver in Fischer Rats with a Normal Copper Metabolism and in Long-Evans Cinnamon Rats with an Abnormal Copper Metabolism 2000; TITLE=Competition Between Copper and Silver in Fischer Rats with a Normal Copper Metabolism and in Long-Evans Cinnamon Rats with an Abnormal Copper Metabolism; AUTHOR=Sugawara,N., and C. Sugawara; DOI=10.1007/s002040000115; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=77817; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2000; ORIGINAL_YEAR=2000; TOXICOLOGICAL_EFFECT=Biochemistry: Metallothionein|Physiology: Volume; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15595007_15595447:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=e72ed973d1822a9f345dfbbd960f681a
ToxValDB_ECOTOX LOEL =2 % Mouse injection acute; 1 days acute LONG_REF=J. Biol. Chem.264(32): 19327-19332 Brissette,L., I. Young, S. Narindrasorasak, R. Kisilevsky, and R. Deeley Differential Induction of the Serum Amyloid A Gene Family in Response to an Inflammatory Agent and to Amyloid-Enhancing Factor 1989; TITLE=Differential Induction of the Serum Amyloid A Gene Family in Response to an Inflammatory Agent and to Amyloid-Enhancing Factor; AUTHOR=Brissette,L., I. Young, S. Narindrasorasak, R. Kisilevsky, and R. Deeley; DOI=10.1016/S0021-9258(19)47305-5; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=92787; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1989; ORIGINAL_YEAR=1989; TOXICOLOGICAL_EFFECT=Biochemistry: Amyloid; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15595443:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=72afdece4af00ed2081a70c99e9c6c0c
ToxValDB_ECOTOX LOEL =1.5 mg/kg bw/day Mouse injection short-term; 3 days short-term LONG_REF=Environ. Res.35:507-515 Sugawara,N., and C. Sugawara Comparative Study of Effect of Acute Administration of Cadmium and Silver on Ceruloplasmin and Metallothionein: Involvement of Disposition of Copper, Iron, and Zinc 1984; TITLE=Comparative Study of Effect of Acute Administration of Cadmium and Silver on Ceruloplasmin and Metallothionein: Involvement of Disposition of Copper, Iron, and Zinc; AUTHOR=Sugawara,N., and C. Sugawara; DOI=10.1016/0013-9351(84)90157-9; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=68037; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1984; ORIGINAL_YEAR=1984; TOXICOLOGICAL_EFFECT=Biochemistry: Copper (Cu) content|Enzyme(s): Ceruloplasmin activity; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity|other; STUDY_GROUP=ECOTOX:15599322:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=aaa130efd5ff2734b977a640e29e8986
ToxValDB_ECOTOX LOEL =0.75 mg/kg bw/day Mouse injection short-term; 5 days short-term LONG_REF=Bull. Environ. Contam. Toxicol.54(5): 751-759 Srivastava,R.C., M.M. Husain, S.K. Srivastava, S.K. Hasan, and A. Lal Effect of Pre-Exposure to Cadmium and Silver on Nickel Induced Toxic Manifestations in Mice: Possible Role of Ceruloplasmin and Metallothionein 1995; TITLE=Effect of Pre-Exposure to Cadmium and Silver on Nickel Induced Toxic Manifestations in Mice: Possible Role of Ceruloplasmin and Metallothionein; AUTHOR=Srivastava,R.C., M.M. Husain, S.K. Srivastava, S.K. Hasan, and A. Lal; DOI=10.1007/BF00206109; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=61399; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1995; ORIGINAL_YEAR=1995; TOXICOLOGICAL_EFFECT=Biochemistry: Metallothionein|Enzyme(s): Ceruloplasmin activity; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity|other; STUDY_GROUP=ECOTOX:15599622:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=49b159d781d3cd976b54c6e4364ddf52
ToxValDB_ECOTOX LOEL =400 mg/L Mouse oral chronic; 426.16 days chronic LONG_REF=J. Toxicol. Environ. Health Part A69(6): 505-523 Hultman,P., A. Taylor, J.M. Yang, and K.M. Pollard The Effect of Xenobiotic Exposure on Spontaneous Autoimmunity in (SWR x SJL)F1 Hybrid Mice 2006; TITLE=The Effect of Xenobiotic Exposure on Spontaneous Autoimmunity in (SWR x SJL)F1 Hybrid Mice; AUTHOR=Hultman,P., A. Taylor, J.M. Yang, and K.M. Pollard; DOI=10.1080/15287390500354904; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=87300; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=2006; ORIGINAL_YEAR=2006; TOXICOLOGICAL_EFFECT=Immunological: Antibody titres; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15603820:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=78922fa82d8039791abf382e6e3a96b6
ToxValDB_ECOTOX LOEL =65 umol/kg/day Rat injection short-term; 1.5 days short-term LONG_REF=Toxicol. Appl. Pharmacol.55(2): 393-402 Eaton,D.L., N.H. Stacey, K.L. Wong, and C.D. Klaassen Dose-Response Effects of Various Metal Ions on Rat Liver Metallothionein, Glutathione, Heme Oxygenase, and Cytochrome P-450 1980; TITLE=Dose-Response Effects of Various Metal Ions on Rat Liver Metallothionein, Glutathione, Heme Oxygenase, and Cytochrome P-450; AUTHOR=Eaton,D.L., N.H. Stacey, K.L. Wong, and C.D. Klaassen; DOI=10.1016/0041-008x(80)90101-5; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=86834; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1980; ORIGINAL_YEAR=1980; TOXICOLOGICAL_EFFECT=Biochemistry: Glutathione (reduced glutathione)|Enzyme(s): Heme oxygenase; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity|other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15607756_15607757:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=759b2e377b01f9e74eadba5a65c4d236
ToxValDB_ECOTOX LOEL =0.0093 mmol/kg Rat injection short-term; 6 days short-term LONG_REF=Toxicol. Lett.70(2): 193-201 Hirasawa,F., M. Sato, and Y. Takizawa Organ Distribution of Silver and the Effect of Silver on Copper Status in Rats 1994; TITLE=Organ Distribution of Silver and the Effect of Silver on Copper Status in Rats; AUTHOR=Hirasawa,F., M. Sato, and Y. Takizawa; DOI=10.1016/0378-4274(94)90163-5; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=86164; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1994; ORIGINAL_YEAR=1994; TOXICOLOGICAL_EFFECT=Accumulation: Residue|Biochemistry: Copper (Cu) content|Enzyme(s): Ceruloplasmin activity; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity|other; STUDY_GROUP=ECOTOX:15608087:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=fbd092029af3aa7b447c6c5fd7b459bd
ToxValDB_ECOTOX NOEC =6.47 mg/org-day Rat oral acute; 1 days acute LONG_REF=Folia Biol. (Prague)26(1): 47-52 Pribyl,T., V. Schreiber, and J. Jahodova Inhibition of Rat Serum Polyphenoloxidase Activity by Silver Ions Abolished by Administration of Copper Ions 1980; TITLE=Inhibition of Rat Serum Polyphenoloxidase Activity by Silver Ions Abolished by Administration of Copper Ions; AUTHOR=Pribyl,T., V. Schreiber, and J. Jahodova; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=69099; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1980; ORIGINAL_YEAR=1980; TOXICOLOGICAL_EFFECT=Enzyme(s): Ceruloplasmin activity; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity; STUDY_GROUP=ECOTOX:15596223:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=a6654bd893f550c56490155e3ddad5c8
ToxValDB_ECOTOX NOEL =1 mg/kg bw/day Mouse injection short-term; 14 days short-term LONG_REF=Biochem. Mol. Biol. Int.30(2): 261-270 Srivastava,R.C., S.K. Hasan, Jyotsana, and S. Gupta Protective Role of Metallothionein in Nickel Induced Oxidative Damage 1993; TITLE=Protective Role of Metallothionein in Nickel Induced Oxidative Damage; AUTHOR=Srivastava,R.C., S.K. Hasan, Jyotsana, and S. Gupta; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=61398; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1993; ORIGINAL_YEAR=1993; TOXICOLOGICAL_EFFECT=Physiology: Lipid peroxidation; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15594652:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=6ad000bd71ac094fcbf5acf62e87f6c0
ToxValDB_ECOTOX NOEL =0.183 mg/kg bw/day Rat injection acute; 1 days acute LONG_REF=J. Hyg. Epidemiol. Microbiol. Immunol.31(1): 39-43 Blaha,K.,Jr., J. Havrdova, J. Rosina, I. Sperlingova, P. Tichy, and M. Cikrt The Effect of Silver-110m Ag on Ceruloplasmin Oxidase Activity in Rats 1987; TITLE=The Effect of Silver-110m Ag on Ceruloplasmin Oxidase Activity in Rats; AUTHOR=Blaha,K.,Jr., J. Havrdova, J. Rosina, I. Sperlingova, P. Tichy, and M. Cikrt; QUALITY=Control type: Concurrent control; EXTERNAL_SOURCE_ID=86335; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1987; ORIGINAL_YEAR=1987; TOXICOLOGICAL_EFFECT=Accumulation: Residue; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15600833:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=30d72f8abd7c7e8cdad51ef358d20aa0
ToxValDB_ECOTOX NOEL =33 umol/kg/day Rat injection short-term; 1.5 days short-term LONG_REF=Toxicol. Appl. Pharmacol.55(2): 393-402 Eaton,D.L., N.H. Stacey, K.L. Wong, and C.D. Klaassen Dose-Response Effects of Various Metal Ions on Rat Liver Metallothionein, Glutathione, Heme Oxygenase, and Cytochrome P-450 1980; TITLE=Dose-Response Effects of Various Metal Ions on Rat Liver Metallothionein, Glutathione, Heme Oxygenase, and Cytochrome P-450; AUTHOR=Eaton,D.L., N.H. Stacey, K.L. Wong, and C.D. Klaassen; DOI=10.1016/0041-008x(80)90101-5; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=86834; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1980; ORIGINAL_YEAR=1980; TOXICOLOGICAL_EFFECT=Biochemistry: Glutathione (reduced glutathione)|Enzyme(s): Heme oxygenase; TOXICOLOGICAL_EFFECT_CATEGORY=enzyme activity|other; STUDY_GROUP=ECOTOX_dup_EPA ORD_15607756_15607757:M:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=275130bc14f73b1a515aafc336dbe207
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =0.016 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634640:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2994f964d2d931d1ca4706cbde3d0943
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 95IT3W8JZE UNII - - - chemical {"approval_status":null,"molecular_formula":"Ag.NO3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"95IT3W8JZE"}
openFDA substances FDA UNII substance identifier 95IT3W8JZE UNII - - - chemical {"approval_status":null,"molecular_formula":"Ag.NO3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"95IT3W8JZE"}
openFDA substances FDA UNII substance identifier 95IT3W8JZE UNII - - - chemical {"approval_status":null,"molecular_formula":"Ag.NO3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"95IT3W8JZE"}
openFDA substances FDA UNII substance identifier 95IT3W8JZE UNII - - - chemical {"approval_status":null,"molecular_formula":"Ag.NO3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"95IT3W8JZE"}