NOAEL Studies Cosmetic Ingredient

Sodium Borohydride NOAEL Studies

INCI: SODIUM BOROHYDRIDE

CAS: 16940-66-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx NOAEL =9.6 mg/kg bw/day Rat oral: feed 21 days reproduction toxicity ENDPOINTSTUDY_ID 690297; TOX_ID 1 - OP_ID 2 - EFSA NDA - 2004 - Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the Tolerable Upper Intake Level of Boron (Sodium Borate and Boric Acid) - doi:10.2903/j.efsa.2004.80
EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx NOAEL =9.6 mg/kg bw/day Rat oral: feed 21 days reproduction toxicity ENDPOINTSTUDY_ID 690297; TOX_ID 1 - OP_ID 2 - EFSA NDA - 2004 - Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the Tolerable Upper Intake Level of Boron (Sodium Borate and Boric Acid) - doi:10.2903/j.efsa.2004.80
NTP_ICE_acute_inhalation 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 >5.18 mg/L - Inhalation Duration=1 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=4871; Record_ID=acute_inhalation_1339; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID80893977; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=5.18; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14382/7/3/3/?documentUUID=d5d2a377-bdbf-4b16-a6e7-ca96971e6317; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID80893977
NTP_ICE_acute_inhalation LC50 0.036 mg/L - Inhalation - In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=4872; Record_ID=acute_inhalation_1388; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID80893977; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=0.036; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID80893977
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =5.1 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634750:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c267a1ab6ff1b617b4a57b0b2f6abcc6
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 87L0B9CPPA UNII - - - chemical {"approval_status":null,"molecular_formula":"Na.BH4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"87L0B9CPPA"}
openFDA substances FDA UNII substance identifier 87L0B9CPPA UNII - - - chemical {"approval_status":null,"molecular_formula":"Na.BH4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"87L0B9CPPA"}
openFDA substances FDA UNII substance identifier 87L0B9CPPA UNII - - - chemical {"approval_status":null,"molecular_formula":"Na.BH4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"87L0B9CPPA"}
openFDA substances FDA UNII substance identifier 87L0B9CPPA UNII - - - chemical {"approval_status":null,"molecular_formula":"Na.BH4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"87L0B9CPPA"}