Sodium Metasilicate
INCI: SODIUM METASILICATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sodium Metasilicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | rabbit | Short Term Toxicity | COSMOS_DB |
| NOAEL | >227 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 260 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | >227 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 260 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 75 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 125 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 125 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 75 mg/kg bw/day | oral | mouse | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Highly alkaline — significant skin/eye irritation risk at higher concentrations; inhalation concern with powdered forms (crystalline silica must be <0.1%); must formulate to avoid irritation per CIR stipulation
Regulatory Flags
Frequently Asked Questions
Is Sodium Metasilicate safe in cosmetics?
Highly alkaline — significant skin/eye irritation risk at higher concentrations; inhalation concern with powdered forms (crystalline silica must be <0.1%); must formulate to avoid irritation per CIR stipulation The EU classifies Sodium Metasilicate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Sodium Metasilicate allowed in the EU?
Sodium Metasilicate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Metasilicate do in cosmetics?
Sodium Metasilicate functions as: Anticorrosive, Buffering, Chelating, Bulking. It is classified as a cosmetic ingredient in our database. CAS number: 6834-92-0.
What is the Margin of Safety for Sodium Metasilicate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Metasilicate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Metasilicate is 200 mg/kg bw/day based on a Short Term Toxicity study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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