Sodium Retinoyl Hyaluronate

INCI: SODIUM RETINOYL HYALURONATE

CAS Number
Not publicly assigned in CosIng (novel biotech ingredient)
Function
Skin conditioning (anti-aging, collagen stimulation, hydration, wrinkle reduction)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; retinoic acid (tretinoin) itself is Rx-only โ€” this ester form is distinct

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Retinoid derivative โ€” monitor for free retinoic acid release. EU Annex II \#375 prohibits retinoic acid itself. Pregnancy advisory applies to all retinoid-class ingredients. Use concentration must stay within tested range

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Concern Level: Low

Frequently Asked Questions

Is Sodium Retinoyl Hyaluronate safe in cosmetics?

Retinoid derivative โ€” monitor for free retinoic acid release. EU Annex II \#375 prohibits retinoic acid itself. Pregnancy advisory applies to all retinoid-class ingredients. Use concentration must stay within tested range The EU classifies Sodium Retinoyl Hyaluronate as "permitted". Safety rating: GOOD.

Is Sodium Retinoyl Hyaluronate allowed in the EU?

Sodium Retinoyl Hyaluronate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Retinoyl Hyaluronate do in cosmetics?

Sodium Retinoyl Hyaluronate functions as: Skin conditioning (anti-aging, collagen stimulation, hydration, wrinkle reduction). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned in CosIng (novel biotech ingredient).

What is the Margin of Safety for Sodium Retinoyl Hyaluronate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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