Sodium Sesquicarbonate

INCI: SODIUM SESQUICARBONATE

CAS Number
533-96-0
Function
Buffering, Bulking, Cleansing
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR concluded safe as used in cosmetics (1987, reaffirmed 2005/2006, reaffirmed 2023/2025). Also GRAS for food use under FDA.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low-risk inorganic buffer and bulking agent with excellent safety profile confirmed across three CIR review cycles spanning nearly 40 years.

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Concern Level: None

Regulatory Flags

epa_safer_alternative fda_food_additive jecfa_safe

Frequently Asked Questions

Is Sodium Sesquicarbonate safe in cosmetics?

Low-risk inorganic buffer and bulking agent with excellent safety profile confirmed across three CIR review cycles spanning nearly 40 years. The EU classifies Sodium Sesquicarbonate as "permitted". Safety rating: EXCELLENT.

Is Sodium Sesquicarbonate allowed in the EU?

Sodium Sesquicarbonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Sesquicarbonate do in cosmetics?

Sodium Sesquicarbonate functions as: Buffering, Bulking, Cleansing. It is classified as a Cosmetic Ingredient in our database. CAS number: 533-96-0.

What is the Margin of Safety for Sodium Sesquicarbonate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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