Sodium Urocanate

INCI: SODIUM UROCANATE

CAS Number
6159-49-5
Function
UV absorber, skin conditioning (sodium salt of urocanic acid, a natural UV-absorbing compound in skin)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not listed as an approved OTC sunscreen active; permitted as cosmetic ingredient for conditioning purposes

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cis-urocanic acid is a known immunosuppressant โ€” UV-induced isomerization is a significant safety concern that has prevented approval as a sunscreen active

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Sodium Urocanate safe in cosmetics?

Cis-urocanic acid is a known immunosuppressant โ€” UV-induced isomerization is a significant safety concern that has prevented approval as a sunscreen active The EU classifies Sodium Urocanate as "permitted". Safety rating: MODERATE.

Is Sodium Urocanate allowed in the EU?

Sodium Urocanate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Urocanate do in cosmetics?

Sodium Urocanate functions as: UV absorber, skin conditioning (sodium salt of urocanic acid, a natural UV-absorbing compound in skin). It is classified as a cosmetic ingredient in our database. CAS number: 6159-49-5.

What is the Margin of Safety for Sodium Urocanate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Sodium Urocanate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Urocanate in your formulation.