Soluble Proteoglycan

INCI: SOLUBLE PROTEOGLYCAN

CAS Number
Not assigned (complex glycoprotein; listed as CAS "0" in China CFDA)
Function
Skin Conditioning, Humectant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific CIR monograph โ€” limited formal safety data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR or SCCS safety assessment available; source-dependent (salmon nasal cartilage is common source โ€” fish allergen risk); purity and MW characterization critical for safety dossier; limited toxicological dataset for regulatory defense

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Soluble Proteoglycan safe in cosmetics?

No CIR or SCCS safety assessment available; source-dependent (salmon nasal cartilage is common source โ€” fish allergen risk); purity and MW characterization critical for safety dossier; limited toxicological dataset for regulatory defense The EU classifies Soluble Proteoglycan as "permitted". Safety rating: MODERATE.

Is Soluble Proteoglycan allowed in the EU?

Soluble Proteoglycan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Soluble Proteoglycan do in cosmetics?

Soluble Proteoglycan functions as: Skin Conditioning, Humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex glycoprotein; listed as CAS "0" in China CFDA).

What is the Margin of Safety for Soluble Proteoglycan?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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