Regulatory Status
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Safety Data
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Expert Verdict
🚫 Pharmacologically active alkaloid — analgesic and anti-inflammatory effects documented in vivo; use only at very low concentrations; potential systemic toxicity at higher doses; no established cosmetic safe-use level; requires robust safety dossier for EU PIF
Frequently Asked Questions
Is Sophocarpine safe in cosmetics?
🚫 Pharmacologically active alkaloid — analgesic and anti-inflammatory effects documented in vivo; use only at very low concentrations; potential systemic toxicity at higher doses; no established cosmetic safe-use level; requires robust safety dossier for EU PIF The EU classifies Sophocarpine as "permitted". Safety rating: MODERATE.
Is Sophocarpine allowed in the EU?
Sophocarpine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sophocarpine do in cosmetics?
Sophocarpine functions as: Skin conditioning agent; bioactive quinolizidine alkaloid from Sophora species. It is classified as a cosmetic ingredient in our database. CAS number: 145-38-0.
What is the Margin of Safety for Sophocarpine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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