Sorbitan Trioleate

INCI: SORBITAN TRIOLEATE

CAS Number
26266-58-0
Function
Surfactant – Emulsifying Agent; HLB 1.8
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted; CIR safe as used (1985, reaffirmed 2014). Also FDA inactive drug ingredient and diluent in color additives (21CFR73.1001)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Historical co-carcinogenesis data: undiluted sorbitan trioleate was active as a co-carcinogen on mouse skin with DMBA. CIR concluded no co-carcinogenesis risk at cosmetic use levels due to high exposure levels in studies and absence of dose-response

⚠️
Concern Level: Moderate

Regulatory Flags

epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is Sorbitan Trioleate safe in cosmetics?

Historical co-carcinogenesis data: undiluted sorbitan trioleate was active as a co-carcinogen on mouse skin with DMBA. CIR concluded no co-carcinogenesis risk at cosmetic use levels due to high exposure levels in studies and absence of dose-response The EU classifies Sorbitan Trioleate as "permitted". Safety rating: GOOD.

Is Sorbitan Trioleate allowed in the EU?

Sorbitan Trioleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sorbitan Trioleate do in cosmetics?

Sorbitan Trioleate functions as: Surfactant – Emulsifying Agent; HLB 1.8. It is classified as a cosmetic ingredient in our database. CAS number: 26266-58-0.

What is the Margin of Safety for Sorbitan Trioleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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