Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Soyalkonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1515.15 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 792 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 40 mg/kg bw/day | dermal | code:3484 | dermal | REACH |
| NOEL | 2800 ppm | oral | dog | oral | REACH |
| NOAEL | 2800 ppm | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Cationic surfactant — potential irritant at elevated concentrations; soy-derived allergen labeling; well-established alkonium chloride class
Regulatory Flags
Frequently Asked Questions
Is Soyalkonium Chloride safe in cosmetics?
Cationic surfactant — potential irritant at elevated concentrations; soy-derived allergen labeling; well-established alkonium chloride class The EU classifies Soyalkonium Chloride as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.
Is Soyalkonium Chloride allowed in the EU?
Soyalkonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Soyalkonium Chloride do in cosmetics?
Soyalkonium Chloride functions as: Antistatic, hair conditioning, surfactant (cationic). It is classified as a cosmetic ingredient in our database. CAS number: 61789-80-8.
What is the Margin of Safety for Soyalkonium Chloride?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Soyalkonium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Soyalkonium Chloride is 1515.15 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 7 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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