Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Steareth-25. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 800 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 800 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Ethoxylated ingredient with potential 1,4-dioxane residues; require supplier COA demonstrating 1,4-dioxane ≤10 ppm (EU expectation) or ≤2 ppm (NY DEC threshold); vacuum stripping can remove residual dioxane.
Regulatory Flags
Frequently Asked Questions
Is Steareth-25 safe in cosmetics?
Ethoxylated ingredient with potential 1,4-dioxane residues; require supplier COA demonstrating 1,4-dioxane ≤10 ppm (EU expectation) or ≤2 ppm (NY DEC threshold); vacuum stripping can remove residual dioxane. The EU classifies Steareth-25 as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Steareth-25 allowed in the EU?
Steareth-25 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Steareth-25 do in cosmetics?
Steareth-25 functions as: Emulsifying, surfactant, cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68439-49-6.
What is the Margin of Safety for Steareth-25?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Steareth-25?
The NOAEL (No Observed Adverse Effect Level) for Steareth-25 is 800 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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