Sucrose Myristate

INCI: SUCROSE MYRISTATE

CAS Number
27216-47-3 / 9042-71-1
Function
Skin conditioning — Emollient, Surfactant — Emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; direct food additive (21CFR172.859); 3 VCRP uses; max concentration 0.1–6%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

In vitro cytotoxicity: 50–75% cell death at 0.1–0.3 mg/mL in LDH assay on nasal epithelial cells. Acts as permeation enhancer — consider this when co-formulating with actives or penetration-sensitive ingredients. Myristic acid reviewed safe by CIR. Melting point 180–186°C.

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Concern Level: Moderate

Frequently Asked Questions

Is Sucrose Myristate safe in cosmetics?

In vitro cytotoxicity: 50–75% cell death at 0.1–0.3 mg/mL in LDH assay on nasal epithelial cells. Acts as permeation enhancer — consider this when co-formulating with actives or penetration-sensitive ingredients. Myristic acid reviewed safe by CIR. Melting point 180–186°C. The EU classifies Sucrose Myristate as "permitted". Safety rating: GOOD.

Is Sucrose Myristate allowed in the EU?

Sucrose Myristate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sucrose Myristate do in cosmetics?

Sucrose Myristate functions as: Skin conditioning — Emollient, Surfactant — Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 27216-47-3 / 9042-71-1.

What is the Margin of Safety for Sucrose Myristate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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