Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for TEA-Cocoyl Glycinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2.5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 0.4 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 0.4 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 2 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1.25 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 10 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 100 ppm | oral | rat | oral | REACH |
| LOAEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 100 ppm | oral | rat | oral | REACH |
| NOAEL | 4 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Nitrosamine risk from TEA; must not combine with nitrosating systems; secondary amine ≤0.5%
Frequently Asked Questions
Is TEA-Cocoyl Glycinate safe in cosmetics?
Nitrosamine risk from TEA; must not combine with nitrosating systems; secondary amine ≤0.5% The EU classifies TEA-Cocoyl Glycinate as "restricted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is TEA-Cocoyl Glycinate allowed in the EU?
TEA-Cocoyl Glycinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does TEA-Cocoyl Glycinate do in cosmetics?
TEA-Cocoyl Glycinate functions as: Surfactant – Cleansing, Foaming, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68911-79-5.
What is the Margin of Safety for TEA-Cocoyl Glycinate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for TEA-Cocoyl Glycinate?
The NOAEL (No Observed Adverse Effect Level) for TEA-Cocoyl Glycinate is 2.5 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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