Is Tetrapeptide-18 safe in cosmetics?
Tetrapeptide-18 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tetrapeptide-18
INCI: TETRAPEPTIDE-18
Tetrapeptide-18 (CAS Not publicly assigned for free form; most commonly encountered as Acetyl Tetrapeptide-18) is a cosmetic cosmetic ingredient functioning as Skin conditioning (anti-wrinkle). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly assigned for free form; most commonly encountered as Acetyl Tetrapeptide-18
View industrial chemical safety profile →
Function
Skin conditioning (anti-wrinkle)
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use; no specific FDA monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrapeptide-18.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Tetrapeptide-18.
Frequently Asked Questions
Is Tetrapeptide-18 allowed in the EU?
Tetrapeptide-18 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrapeptide-18 do in cosmetics?
Tetrapeptide-18 functions as: Skin conditioning (anti-wrinkle). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for free form; most commonly encountered as Acetyl Tetrapeptide-18.
Compliance Tools
Check Tetrapeptide-18 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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