Tetrapeptide-68

INCI: TETRAPEPTIDE-68

CAS Number
Not publicly listed (sequence: GQVS, MW: 317.18 Da)
Function
Anti-wrinkle; elastase inhibitory activity; promotes skin cell proliferation; supports collagen and elastin synthesis
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA monograph; general cosmetic ingredient status

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Derived from Loricrin (endogenous skin structural protein). Only one published clinical study (n=25, Korean population). No CIR/SCCS formal review. Study funded by manufacturer (A\&PEP Inc.) โ€” note conflict of interest

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Concern Level: Low

Frequently Asked Questions

Is Tetrapeptide-68 safe in cosmetics?

Derived from Loricrin (endogenous skin structural protein). Only one published clinical study (n=25, Korean population). No CIR/SCCS formal review. Study funded by manufacturer (A\&PEP Inc.) โ€” note conflict of interest The EU classifies Tetrapeptide-68 as "permitted". Safety rating: GOOD.

Is Tetrapeptide-68 allowed in the EU?

Tetrapeptide-68 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetrapeptide-68 do in cosmetics?

Tetrapeptide-68 functions as: Anti-wrinkle; elastase inhibitory activity; promotes skin cell proliferation; supports collagen and elastin synthesis. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed (sequence: GQVS, MW: 317.18 Da).

What is the Margin of Safety for Tetrapeptide-68?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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