| ECHA |
LEL |
=3 |
mg/kg bw/day |
Rat |
injection |
- |
acute |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61bf1e4b096bca877004d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/3/5?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15815096:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5eb12ec75d2152c7a3ab2c2b4972dd21 |
| ECHA |
LEL |
=25 |
mg/kg bw/day |
Rat |
oral |
- |
repeat dose other |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9bf1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15849649:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_ca7c98dd9b77d1d5408dffaa3f69ecdc |
| ECHA |
LEL |
=131 |
mg/kg bw/day |
Rat |
oral |
short-term; 10 days |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d22645e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15844751_15844752:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7c5a3f97421a9b0c679bf45529bf692c |
| ECHA |
LEL |
=557.5 |
mg/kg bw/day |
Rat |
oral |
- |
chronic |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa0ce4b0a7c65d1b40a6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/8?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15820480:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_e3656b8fb56cfbd13e1627d1b6e0e24e |
| ECHA |
LOAEC |
=2000 |
ppm |
Rat |
oral |
- |
developmental |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d1ece4b0a7c65d230cfc; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/9/3?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15821828:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_cb09510aca3a1e6f92a4c7060c6713e3 |
| ECHA |
LOAEL |
~20 |
mg/kg bw/day |
Rat |
oral |
short-term; 14 days |
short-term |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d22643d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=body weight and weight gain; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832274_15849651:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_2505bfe06eae350f6cbd4ef149f830fe |
| ECHA |
LOAEL |
~21 |
mg/kg bw/day |
Rat |
oral |
short-term; 14 days |
short-term |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d22643d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=body weight and weight gain; TOXICOLOGICAL_EFFECT_CATEGORY=body weight; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832275_15849650:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_2512124dac882f2cbc2a322f4ee7a23c |
| ECHA |
LOAEL |
=30 |
mg/kg bw/day |
Rat |
oral |
subchronic; 8 weeks |
subchronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9bfd; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=body weight and weight gain|food efficiency; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|other; STUDY_GROUP=ECHA IUCLID:15847759:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_8b7c942fd866b3abe8c55f2eea17e283 |
| ECHA |
LOAEL |
=50 |
mg/kg bw/day |
Rat |
oral |
- |
chronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa0ce4b0a7c65d1b40aa; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/8?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=histopathology: neoplastic; TOXICOLOGICAL_EFFECT_CATEGORY=cancer; STUDY_GROUP=ECHA IUCLID_dup_Carcinogenicity_15819476_15820481:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_186ecceca6c95c43bf03e872a4363291 |
| ECHA |
LOAEL |
~55 |
mg/kg bw/day |
Rat |
oral |
short-term; 14 days |
short-term |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d226422; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832274_15849651:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_657ead3c6e4138e4666661d2b871e965 |
| ECHA |
LOAEL |
~59 |
mg/kg bw/day |
Rat |
oral |
short-term; 14 days |
short-term |
QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d226422; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832275_15849650:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a6b721a4bce48fd31bdf89308e77a2a6 |
| ECHA |
LOAEL |
<300 |
mg/kg bw/day |
Rat |
oral |
- |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d22642e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=haematology|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=hematology|organ weight; STUDY_GROUP=ECHA IUCLID:15832358:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b8ccf21298edc3743f1e64138d6a414d |
| ECHA |
LOEL |
~70 |
mg/kg bw/day |
Rat |
oral |
short-term; 10 days |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d226441; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15844690:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7ad227f56f2f3cf0b6a22becd65c5a35 |
| ECHA |
NOAEL |
=25 |
mg/kg bw/day |
Rat |
oral |
- |
chronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa0ce4b0a7c65d1b40aa; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/8?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; TOXICOLOGICAL_EFFECT=mortality; TOXICOLOGICAL_EFFECT_CATEGORY=mortality/survival; STUDY_GROUP=ECHA IUCLID_dup_Carcinogenicity_15819476_15820481:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_cce8edb855950150933262f45989db55 |
| ECHA |
NOAEL |
>=27.5 |
mg/kg bw/day |
Rat |
oral |
chronic; 53 weeks |
chronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9bef; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15847465:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_ec4bcd4f21d52089c27fd2ddfb46d8f4 |
| ECHA |
NOEL |
>=1.73 |
mg/kg bw/day |
Rat |
oral |
subchronic; 13 weeks |
subchronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9be1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15849646:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_e2bf31f922f6c429fe9d28f579399013 |
| ECHA |
NOEL |
>=2.65 |
mg/kg bw/day |
Rat |
oral |
subchronic; 13 weeks |
subchronic |
QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9be1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID:15849647:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_981b2dc264d23f791dd4cdf234c8b186 |
| ECHA |
NOEL |
=12 |
mg/kg bw/day |
Rat |
oral |
short-term; 10 days |
short-term |
QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb77e4b0a7c65d22645e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11868/7/6/2?documentUUID=f3b36df7-fd40-469e-9aa4-485816fd292d; YEAR=1985; ORIGINAL_YEAR=1985; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15844751_15844752:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_804459252a2813fec85aeef3f7a6aa7d |