Tinospora cordifolia Root Extract

INCI: TINOSPORA CORDIFOLIA ROOT EXTRACT

CAS Number
Not specifically assigned (botanical extract); parent plant CAS: 90131-61-6 applies to stem
Function
Skin conditioning, antioxidant (Guduchi/Giloy traditional use)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; no CIR safety review published

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR or SCCS safety assessment; alkaloid content (berberine, tinosporin) requires characterization; hepatoprotective claims need substantiation for cosmetic marketing

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Tinospora cordifolia Root Extract safe in cosmetics?

No CIR or SCCS safety assessment; alkaloid content (berberine, tinosporin) requires characterization; hepatoprotective claims need substantiation for cosmetic marketing The EU classifies Tinospora cordifolia Root Extract as "permitted". Safety rating: MODERATE.

Is Tinospora cordifolia Root Extract allowed in the EU?

Tinospora cordifolia Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tinospora cordifolia Root Extract do in cosmetics?

Tinospora cordifolia Root Extract functions as: Skin conditioning, antioxidant (Guduchi/Giloy traditional use). It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (botanical extract); parent plant CAS: 90131-61-6 applies to stem.

What is the Margin of Safety for Tinospora cordifolia Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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