Tinospora crispa Stem Extract

INCI: TINOSPORA CRISPA STEM EXTRACT

CAS Number
Not specifically assigned (botanical CAS pending)
Function
Skin conditioning, antioxidant (high radical scavenging activity by ESR)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains protoberberine alkaloids and diterpene lactones (borapetoside); stimulates laminin-5 synthesis per patent claims ; no formal safety dossier; specify extraction solvent in MSDS

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Tinospora crispa Stem Extract safe in cosmetics?

Contains protoberberine alkaloids and diterpene lactones (borapetoside); stimulates laminin-5 synthesis per patent claims ; no formal safety dossier; specify extraction solvent in MSDS The EU classifies Tinospora crispa Stem Extract as "permitted". Safety rating: MODERATE.

Is Tinospora crispa Stem Extract allowed in the EU?

Tinospora crispa Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tinospora crispa Stem Extract do in cosmetics?

Tinospora crispa Stem Extract functions as: Skin conditioning, antioxidant (high radical scavenging activity by ESR). It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (botanical CAS pending).

What is the Margin of Safety for Tinospora crispa Stem Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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