Tocopheryl Tranexamate HCl

INCI: TOCOPHERYL TRANEXAMATE HCL

CAS Number
Proprietary/not widely published; conjugate of tocopherol + tranexamic acid HCl salt
Function
Skin Conditioning, Skin Lightening (combines vitamin E antioxidant activity with tranexamic acid's anti-melanogenic action)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA cosmetic restriction; tranexamic acid itself is an OTC drug in some applications โ€” as a cosmetic ester conjugate, classification depends on claims

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual-active ingredient โ€” if making brightening/lightening claims, US FDA may classify as drug. Ensure claims stay within cosmetic boundaries. Limited published peer-reviewed safety data

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Concern Level: Moderate

Frequently Asked Questions

Is Tocopheryl Tranexamate HCl safe in cosmetics?

Dual-active ingredient โ€” if making brightening/lightening claims, US FDA may classify as drug. Ensure claims stay within cosmetic boundaries. Limited published peer-reviewed safety data The EU classifies Tocopheryl Tranexamate HCl as "permitted". Safety rating: MODERATE.

Is Tocopheryl Tranexamate HCl allowed in the EU?

Tocopheryl Tranexamate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tocopheryl Tranexamate HCl do in cosmetics?

Tocopheryl Tranexamate HCl functions as: Skin Conditioning, Skin Lightening (combines vitamin E antioxidant activity with tranexamic acid's anti-melanogenic action). It is classified as a cosmetic ingredient in our database. CAS number: Proprietary/not widely published; conjugate of tocopherol + tranexamic acid HCl salt.

What is the Margin of Safety for Tocopheryl Tranexamate HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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