Tocoquinone

INCI: TOCOQUINONE

CAS Number
7559-04-8 (α-tocoquinone / tocopherolquinone)
Function
Antioxidant, Skin Conditioning (oxidized metabolite of tocopherol)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Quinone moiety — quinones can be pro-oxidant under certain conditions. Stability in formulations should be verified. Very limited commercial cosmetic use data available

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Tocoquinone safe in cosmetics?

Quinone moiety — quinones can be pro-oxidant under certain conditions. Stability in formulations should be verified. Very limited commercial cosmetic use data available The EU classifies Tocoquinone as "permitted". Safety rating: MODERATE.

Is Tocoquinone allowed in the EU?

Tocoquinone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tocoquinone do in cosmetics?

Tocoquinone functions as: Antioxidant, Skin Conditioning (oxidized metabolite of tocopherol). It is classified as a cosmetic ingredient in our database. CAS number: 7559-04-8 (α-tocoquinone / tocopherolquinone).

What is the Margin of Safety for Tocoquinone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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