Trapa japonica Callus Extract

INCI: TRAPA JAPONICA CALLUS EXTRACT

CAS Number
Not assigned (biotechnology-derived botanical extract)
Function
Skin conditioning / Antioxidant — callus cultures used for consistent bioactive production
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; no specific restriction; treated as a botanical/biotech cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel biotech ingredient with limited long-term human safety data; cell culture origin requires validated process consistency; ensure absence of plant growth regulators and residual culture media components; *T. japonica* fruit shows promising cell proliferation effects on dermal papilla cells

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Concern Level: Low

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Trapa japonica Callus Extract safe in cosmetics?

Novel biotech ingredient with limited long-term human safety data; cell culture origin requires validated process consistency; ensure absence of plant growth regulators and residual culture media components; *T. japonica* fruit shows promising cell proliferation effects on dermal papilla cells The EU classifies Trapa japonica Callus Extract as "permitted". Safety rating: GOOD.

Is Trapa japonica Callus Extract allowed in the EU?

Trapa japonica Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trapa japonica Callus Extract do in cosmetics?

Trapa japonica Callus Extract functions as: Skin conditioning / Antioxidant — callus cultures used for consistent bioactive production. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (biotechnology-derived botanical extract).

What is the Margin of Safety for Trapa japonica Callus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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