Trifluoromethyl Dehydrolatanoprost

INCI: TRIFLUOROMETHYL DEHYDROLATANOPROST (REFERENCED IN EU REGULATORY CALL FOR DATA)

CAS Number
Not publicly assigned for cosmetic use; related to latanoprost prostaglandin analogues
Function
Prostaglandin analogue — eyelash growth stimulation
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Prostaglandin analogues in cosmetics occupy a grey area; FDA considers eyelash growth claims potentially drug claims

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Usage banned by major retailers. Prostaglandin analogues can cause iris darkening, periorbital fat atrophy, and changes in eyelash growth patterns. EU is actively collecting safety data for potential Annex II listing

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Concern Level: High

Frequently Asked Questions

Is Trifluoromethyl Dehydrolatanoprost safe in cosmetics?

Usage banned by major retailers. Prostaglandin analogues can cause iris darkening, periorbital fat atrophy, and changes in eyelash growth patterns. EU is actively collecting safety data for potential Annex II listing The EU classifies Trifluoromethyl Dehydrolatanoprost as "permitted". Safety rating: POOR.

Is Trifluoromethyl Dehydrolatanoprost allowed in the EU?

Trifluoromethyl Dehydrolatanoprost EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trifluoromethyl Dehydrolatanoprost do in cosmetics?

Trifluoromethyl Dehydrolatanoprost functions as: Prostaglandin analogue — eyelash growth stimulation. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for cosmetic use; related to latanoprost prostaglandin analogues.

What is the Margin of Safety for Trifluoromethyl Dehydrolatanoprost?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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