Trifluoropropyl Cyclotetrasiloxane

INCI: TRIFLUOROPROPYL CYCLOTETRASILOXANE (LISTED IN COSING)

CAS Number
Not individually assigned in major databases; related to D4 cyclotetrasiloxane class
Function
Hair Conditioning, Skin Conditioning (fluorinated cyclic siloxane)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

D4 is classified as SVHC (Substance of Very High Concern) in EU. Reproductive toxicant Cat 2; PBT substance. The trifluoropropyl variant needs independent assessment โ€” do not assume equivalence with unmodified D4 regulatory status

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Concern Level: High

Frequently Asked Questions

Is Trifluoropropyl Cyclotetrasiloxane safe in cosmetics?

D4 is classified as SVHC (Substance of Very High Concern) in EU. Reproductive toxicant Cat 2; PBT substance. The trifluoropropyl variant needs independent assessment โ€” do not assume equivalence with unmodified D4 regulatory status The EU classifies Trifluoropropyl Cyclotetrasiloxane as "permitted". Safety rating: MODERATE.

Is Trifluoropropyl Cyclotetrasiloxane allowed in the EU?

Trifluoropropyl Cyclotetrasiloxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trifluoropropyl Cyclotetrasiloxane do in cosmetics?

Trifluoropropyl Cyclotetrasiloxane functions as: Hair Conditioning, Skin Conditioning (fluorinated cyclic siloxane). It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned in major databases; related to D4 cyclotetrasiloxane class.

What is the Margin of Safety for Trifluoropropyl Cyclotetrasiloxane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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