Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine

INCI: TRIMETHYL TRIFLUOROMETHYLINDOLINO PIPERIDINYLSPIRONAPHTHOOXAZINE

CAS Number
Related to photochromic spironaphthooxazine class; closest match CAS 114747-45-4 (non-fluorinated analog)
Function
Not yet officially reported/specified in CosIng — likely UV-responsive photochromic agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA listing or restriction; novel specialty ingredient with limited regulatory history

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major data gap — function not officially classified; contains trifluoromethyl group (fluorinated chemistry); no published toxicological assessment; synthetic photochromic dye — treat with high caution for cosmetic formulation; requires independent safety assessment before use

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Concern Level: High

Frequently Asked Questions

Is Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine safe in cosmetics?

Major data gap — function not officially classified; contains trifluoromethyl group (fluorinated chemistry); no published toxicological assessment; synthetic photochromic dye — treat with high caution for cosmetic formulation; requires independent safety assessment before use The EU classifies Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine as "permitted". Safety rating: MODERATE.

Is Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine allowed in the EU?

Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine do in cosmetics?

Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine functions as: Not yet officially reported/specified in CosIng — likely UV-responsive photochromic agent. It is classified as a cosmetic ingredient in our database. CAS number: Related to photochromic spironaphthooxazine class; closest match CAS 114747-45-4 (non-fluorinated analog).

What is the Margin of Safety for Trimethyl Trifluoromethylindolino Piperidinylspironaphthooxazine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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