Trimethylsiloxy/Polymethylsilsesquioxane

INCI: TRIMETHYLSILOXY/POLYMETHYLSILSESQUIOXANE

CAS Number
Not definitively assigned as a single CAS; base component polymethylsilsesquioxane is 68554-70-1
Function
Anticaking, Binding, Skin Conditioning, Emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; reported in VCRP; CIR reviewed polysilsesquioxanes as safe in present practices of use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Inhalation exposure concern mitigated by large particle sizes (60โ€“80 ยตm); data insufficient for airbrush delivery

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Concern Level: Low

Frequently Asked Questions

Is Trimethylsiloxy/Polymethylsilsesquioxane safe in cosmetics?

Inhalation exposure concern mitigated by large particle sizes (60โ€“80 ยตm); data insufficient for airbrush delivery The EU classifies Trimethylsiloxy/Polymethylsilsesquioxane as "permitted". Safety rating: GOOD.

Is Trimethylsiloxy/Polymethylsilsesquioxane allowed in the EU?

Trimethylsiloxy/Polymethylsilsesquioxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethylsiloxy/Polymethylsilsesquioxane do in cosmetics?

Trimethylsiloxy/Polymethylsilsesquioxane functions as: Anticaking, Binding, Skin Conditioning, Emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not definitively assigned as a single CAS; base component polymethylsilsesquioxane is 68554-70-1.

What is the Margin of Safety for Trimethylsiloxy/Polymethylsilsesquioxane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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