Tris-Hydroxymethylnitromethane

INCI: TRIS-HYDROXYMETHYLNITROMETHANE

CAS Number
126-11-4
Function
Antimicrobial / Preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formaldehyde releaser; banned in leave-on products in the EU; potential sensitizer for formaldehyde-sensitive individuals

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Concern Level: High

Regulatory Flags

potential-allergen preservative

Frequently Asked Questions

Is Tris-Hydroxymethylnitromethane safe in cosmetics?

Formaldehyde releaser; banned in leave-on products in the EU; potential sensitizer for formaldehyde-sensitive individuals The EU classifies Tris-Hydroxymethylnitromethane as "prohibited". Safety rating: MODERATE.

Is Tris-Hydroxymethylnitromethane allowed in the EU?

Tris-Hydroxymethylnitromethane EU regulatory status: prohibited. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Tris-Hydroxymethylnitromethane do in cosmetics?

Tris-Hydroxymethylnitromethane functions as: Antimicrobial / Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 126-11-4.

What is the Margin of Safety for Tris-Hydroxymethylnitromethane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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