Trolox

INCI: TROLOX (6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID)

CAS Number
53188-07-1
Function
Skin conditioning, antioxidant (water-soluble vitamin E analogue)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; widely used in pharmaceutical and cosmetic research

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primarily a research chemical repurposed for cosmetics. Limited long-term dermal safety studies specifically for cosmetic leave-on applications. Store away from light โ€” photodegradable

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Concern Level: Low

Frequently Asked Questions

Is Trolox safe in cosmetics?

Primarily a research chemical repurposed for cosmetics. Limited long-term dermal safety studies specifically for cosmetic leave-on applications. Store away from light โ€” photodegradable The EU classifies Trolox as "permitted". Safety rating: GOOD.

Is Trolox allowed in the EU?

Trolox EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trolox do in cosmetics?

Trolox functions as: Skin conditioning, antioxidant (water-soluble vitamin E analogue). It is classified as a cosmetic ingredient in our database. CAS number: 53188-07-1.

What is the Margin of Safety for Trolox?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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