Moderate Cosmetic Ingredient

Troloxoyl Nonapeptide-38

INCI: TROLOXOYL NONAPEPTIDE-38

CAS Number
Not assigned (novel peptide conjugate)
Function
Skin conditioning, antioxidant (Trolox conjugated with Nonapeptide-38)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; no specific monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel/niche ingredient with extremely limited published safety data. No independent toxicological assessment. Supplier must provide a full safety dossier including dermal irritation/sensitization patch test data, stability data, and microbiological challenge results before incorporation into any formulation

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Troloxoyl Nonapeptide-38 safe in cosmetics?

Novel/niche ingredient with extremely limited published safety data. No independent toxicological assessment. Supplier must provide a full safety dossier including dermal irritation/sensitization patch test data, stability data, and microbiological challenge results before incorporation into any formulation The EU classifies Troloxoyl Nonapeptide-38 as "permitted". Safety rating: MODERATE.

Is Troloxoyl Nonapeptide-38 allowed in the EU?

Troloxoyl Nonapeptide-38 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Troloxoyl Nonapeptide-38 do in cosmetics?

Troloxoyl Nonapeptide-38 functions as: Skin conditioning, antioxidant (Trolox conjugated with Nonapeptide-38). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (novel peptide conjugate).

What is the Margin of Safety for Troloxoyl Nonapeptide-38?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Troloxoyl Nonapeptide-38 compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Aspergillus/Sorghum Bicolor Ferment Lees Extract
Moderate
Protea Obtusifolia Flower Extract
Moderate
Pelvetia Canaliculata Extract
Good
Dilauroyl 3-Glyceryl Ascorbate
Good
Ficus Deltoidea Leaf Extract
Moderate
Browse all 30,000+ ingredients →
📱

Is Troloxoyl Nonapeptide-38 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Troloxoyl Nonapeptide-38 in your formulation.

Ingredient Decoder MoS Calculator