Troloxoyl SH-Pentapeptide-12 SP

INCI: TROLOXOYL SH-PENTAPEPTIDE-12 SP

CAS Number
Not assigned (synthetic peptide conjugate)
Function
Skin conditioning — promotes collagen synthesis, mimics botulinum toxin-like activity for anti-wrinkle effects
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Botulinum toxin-mimetic mechanism warrants careful concentration control; limited long-term data

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Concern Level: Low

Frequently Asked Questions

Is Troloxoyl SH-Pentapeptide-12 SP safe in cosmetics?

Botulinum toxin-mimetic mechanism warrants careful concentration control; limited long-term data The EU classifies Troloxoyl SH-Pentapeptide-12 SP as "permitted". Safety rating: GOOD.

Is Troloxoyl SH-Pentapeptide-12 SP allowed in the EU?

Troloxoyl SH-Pentapeptide-12 SP EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Troloxoyl SH-Pentapeptide-12 SP do in cosmetics?

Troloxoyl SH-Pentapeptide-12 SP functions as: Skin conditioning — promotes collagen synthesis, mimics botulinum toxin-like activity for anti-wrinkle effects. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (synthetic peptide conjugate).

What is the Margin of Safety for Troloxoyl SH-Pentapeptide-12 SP?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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