Vitex Agnus Castus Extract

INCI: VITEX AGNUS CASTUS EXTRACT (NOTE: CORRECTED BOTANICAL INCI IS VITEX AGNUS-CASTUS EXTRACT)

CAS Number
91722-47-3
Function
Astringent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains iridoids and diterpenes with hormonal activity (agnuside, rotundifuran); potential endocrine-modulating effects at oral doses โ€” topical risk considered minimal

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Vitex Agnus Castus Extract safe in cosmetics?

Contains iridoids and diterpenes with hormonal activity (agnuside, rotundifuran); potential endocrine-modulating effects at oral doses โ€” topical risk considered minimal The EU classifies Vitex Agnus Castus Extract as "permitted". Safety rating: GOOD.

Is Vitex Agnus Castus Extract allowed in the EU?

Vitex Agnus Castus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Vitex Agnus Castus Extract do in cosmetics?

Vitex Agnus Castus Extract functions as: Astringent. It is classified as a cosmetic ingredient in our database. CAS number: 91722-47-3.

What is the Margin of Safety for Vitex Agnus Castus Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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