NOAEL Studies Cosmetic Ingredient

Vitis Vinifera Skin Powder NOAEL Studies

INCI: VITIS VINIFERA (GRAPE) SKIN POWDER

CAS: 85594-37-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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CIR Safety Assessment 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL >2 g/kg rat oral 14 days oral toxicity 14; 3; 12, p.15
CIR Safety Assessment NOAEL =50 mg/kg bw/d rat oral 47 D inhalation toxicity 45; 46; 954, p.11
CIR Safety Assessment NOAEL =300 mg/kg/d rat oral 28 days oral toxicity 6; (300; 28, p.10
CIR Safety Assessment NOAEL =2150 mg/kg bw/d rat oral 90 days repeated dose toxicity 2; 5; 7, p.16
Regulatory source 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source inhalation toxicity 50 mg/kg bw/d rat oral 47 D inhalation toxicity p.11
Regulatory source oral toxicity >2 g/kg rat oral 14 days oral toxicity p.15
Regulatory source oral toxicity 300 mg/kg/d rat oral 28 days oral toxicity p.10
Regulatory source repeated dose toxicity 2150 mg/kg bw/d rat oral 90 days repeated dose toxicity p.16
Regulatory source repeated dose toxicity 2150 mg/kg bw/d rat oral 3-week repeated dose toxicity p.19
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 3GOV20705G UNII - - - structurallyDiverse -