Yellow Gentian Root Extract

INCI: GENTIANA LUTEA ROOT EXTRACT

CAS Number
97676-22-7
Function
Skin conditioning (miscellaneous), anti-inflammatory, antioxidant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted. Not on FDA's prohibited/restricted list. Subject to general safety requirements under FD&C Act and MoCRA.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains bitter alkaloids (gentianine) in trace amounts; ensure extract is free from pyrrolizidine alkaloid contamination if wild-harvested. Inhibits tyrosinase—monitor for unintended depigmentation at high concentrations.

⚠️
Concern Level: Low

Regulatory Flags

plant-extract ifra_fragrance

Frequently Asked Questions

Is Yellow Gentian Root Extract safe in cosmetics?

Contains bitter alkaloids (gentianine) in trace amounts; ensure extract is free from pyrrolizidine alkaloid contamination if wild-harvested. Inhibits tyrosinase—monitor for unintended depigmentation at high concentrations. The EU classifies Yellow Gentian Root Extract as "permitted". Safety rating: GOOD.

Is Yellow Gentian Root Extract allowed in the EU?

Yellow Gentian Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Yellow Gentian Root Extract do in cosmetics?

Yellow Gentian Root Extract functions as: Skin conditioning (miscellaneous), anti-inflammatory, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 97676-22-7.

What is the Margin of Safety for Yellow Gentian Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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