Oridonin
CAS 28957-04-2
Oridonin (CAS 28957-04-2) is a pharmaceutical compound with 5 bioactivity targets and 0 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | IC50 | 15363.971046511628 nM | 171 | - |
| - | EC50 | 14421.07142857143 nM | 28 | - |
| - | MIC | 48 ug.mL-1 | 3 | - |
| - | GI50 | 453 nM | 1 | - |
| - | IC50 | 4 ug.mL-1 | 1 | - |
IUPHAR Ligand-Target Data
Curated ligand-target interaction rows with action, affinity, and literature identifiers.
| Target | Action | Affinity | PubMed |
|---|---|---|---|
| AKT serine/threonine kinase 1 AKT1 |
Inhibition | 5.079999923706055 pIC50 | 29695636 |
| AKT serine/threonine kinase 2 AKT2 |
Inhibition | 5.050000190734863 pIC50 | 29695636 |
| BB 3 receptor BRS3 |
Agonist | 6.619999885559082 pEC50 | 35405616 |
| NLRP3 NLRP3 |
Inhibition | 7.28000020980835 pKd | 29959312 |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Oridonin used for in pharmaceutical contexts?
Oridonin (CAS 28957-04-2) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Oridonin?
No adverse-event association or SIDER side-effect rows are rendered for Oridonin in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Oridonin also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for ORIDONIN with EU status "permitted".
What clinical phase is Oridonin in?
No phase 1-4 clinical development badge is rendered for Oridonin because the matched compound identifier rows do not contain a max-phase value.