TopicalDosed ingredientTherapeutic flag Cosmetic cross-reference

Gentian Violet

CAS 548-62-9

Gentian Violet (CAS 548-62-9) is a Phase 4 pharmaceutical compound with 27 bioactivity targets and 16 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
36
SOURCE DrugCentral
Adverse signals
16
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Gentian Violet
CAS Number
548-62-9
UNII
J4Z741D6O5
InChIKey
ZXJXZNDDNMQXFV-UHFFFAOYSA-M
ChEMBL ID
CHEMBL64894
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
dosed ingredientnatural producttherapeutic flagtopicalwithdrawn flag
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 4 (Approved)
Approved or marketed human pharmaceutical use is represented in the source phase field.
ChEMBL CHEMBL64894 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

SOURCE EMBL-EBI ChEMBL 36 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- Potency 14222.321485714285 nM 135 -
- IC50 6087.422068965517 nM 57 -
- GI50 183.05563636363635 nM 55 -
- MIC 216.1601923076923 ug.mL-1 52 -
- AC50 11642.908823529413 nM 34 -
- Ki 1175.12 nM 25 -
- EC50 96.215 nM 2 -
- IC50 7.5 ug.mL-1 1 -
- Kd 830 nM 1 -
Mu-type opioid receptor
GPCR
Ki 6.06 - Homo sapiens
D(1A) dopamine receptor
GPCR
Ki 5.809 - Homo sapiens
D(2) dopamine receptor
GPCR
Ki 5.975 - Homo sapiens
Adenosine receptor A2a
GPCR
Ki 5.724 - Homo sapiens
Alpha-2A adrenergic receptor
GPCR
Ki 6.697 - Homo sapiens
Cytochrome P450 3A4
Enzyme
IC50 5.44 - Homo sapiens
5-hydroxytryptamine receptor 2A
GPCR
Ki 6.124 - Homo sapiens
Alpha-2B adrenergic receptor
GPCR
Ki 6.241 - Homo sapiens
D(3) dopamine receptor
GPCR
Ki 6.55 - Homo sapiens
Histamine H2 receptor
GPCR
Ki 5.945 - Homo sapiens
Muscarinic acetylcholine receptor M1
GPCR
Ki 6.578 - Homo sapiens
Muscarinic acetylcholine receptor M2
GPCR
Ki 6.294 - Homo sapiens
Muscarinic acetylcholine receptor M3
GPCR
Ki 6.037 - Homo sapiens
Muscarinic acetylcholine receptor M4
GPCR
Ki 6.854 - Homo sapiens
Muscarinic acetylcholine receptor M5
GPCR
Ki 6.416 - Homo sapiens
Alpha-2C adrenergic receptor
GPCR
Ki 6.562 - Homo sapiens
Sodium-dependent dopamine transporter
Transporter
Ki 5.49 - Homo sapiens
Cytochrome P450 2D6
Enzyme
IC50 6.084 - Homo sapiens
Adenosine receptor A3
GPCR
Ki 5.628 - Homo sapiens
Alpha-1D adrenergic receptor
GPCR
Ki 6.012 - Homo sapiens
Kappa-type opioid receptor
GPCR
Ki 6.21 - Homo sapiens
Acetylcholinesterase
Enzyme
IC50 5.233 - Homo sapiens
Epidermal growth factor receptor
Kinase
IC50 6.325 - Homo sapiens
Tyrosine-protein kinase Fyn
Kinase
IC50 5.668 - Homo sapiens
Substance-K receptor
GPCR
Ki 6.252 - Homo sapiens
Androgen receptor
Transcription factor
Ki 5.43 - Rattus norvegicus
Alpha-1B adrenergic receptor
GPCR
Ki 5.701 - Rattus norvegicus
SOURCE NLM RxNorm 2 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
GENTIAN VIOLET 4778 SU MTHSPL
gentian violet 4778 IN RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Gentian Violet used for in pharmaceutical contexts?

Gentian Violet (CAS 548-62-9) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Gentian Violet?

Gentian Violet has 16 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Drug ineffective, Drug resistance, Ear infection, Hallucination, Intentional product use issue. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Gentian Violet also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Basic Violet 3 with EU status "prohibited".

What clinical phase is Gentian Violet in?

Gentian Violet is rendered with ChEMBL max phase 4 (approved).

What bioactivity targets are documented for Gentian Violet?

Gentian Violet has 36 bioactivity rows in this page query. Rendered target entries include Mu-type opioid receptor, D(1A) dopamine receptor, D(2) dopamine receptor, Adenosine receptor A2a, Alpha-2A adrenergic receptor.