Aspartic Acid
CAS 56-84-8
Aspartic Acid (CAS 56-84-8) is a Phase 3 pharmaceutical compound with 17 bioactivity targets and 2 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Clinical Development Phase
Highest clinical development phase rendered from the matched compound identifier rows.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | AC50 | 30050.711875 nM | 32 | - |
| - | Potency | 27635.076470588236 nM | 14 | - |
| - | IC50 | 15684.688 nM | 6 | - |
| - | Kd | 32.333333333333336 nM | 3 | - |
| - | Ki | 45350 nM | 2 | - |
| - | EC50 | 15000 nM | 1 | - |
| Calcium-binding mitochondrial carrier protein Aralar1 Transporter |
- | - | - | Homo sapiens |
| Aspartate aminotransferase, cytoplasmic Enzyme |
- | - | - | Homo sapiens |
| Aspartoacylase Enzyme |
- | - | - | Homo sapiens |
| Asparagine synthetase [glutamine-hydrolyzing] Enzyme |
- | - | - | Homo sapiens |
| Argininosuccinate synthase Enzyme |
- | - | - | Homo sapiens |
| Aminoacylase-1 Enzyme |
- | - | - | Homo sapiens |
| Aspartate aminotransferase, mitochondrial Enzyme |
- | - | - | Homo sapiens |
| Aspartate--tRNA ligase, cytoplasmic Enzyme |
- | - | - | Homo sapiens |
| Aspartyl/asparaginyl beta-hydroxylase Enzyme |
- | - | - | Homo sapiens |
| Excitatory amino acid transporter 1 Transporter |
IC50 | 5.03 | - | Homo sapiens |
| Excitatory amino acid transporter 2 Transporter |
IC50 | 4.5 | - | Homo sapiens |
| Excitatory amino acid transporter 3 Transporter |
IC50 | 4.71 | - | Homo sapiens |
| Calcium-binding mitochondrial carrier protein Aralar2 Transporter |
- | - | - | Homo sapiens |
| Glutamate NMDA receptor Ion channel |
IC50 | 5.79 | - | Rattus norvegicus |
| Excitatory amino acid transporter 4 Transporter |
IC50 | 4.96 | - | Rattus norvegicus |
| Glutamate transporter homolog Transporter |
Kd | 9 | - | Pyrococcus horikoshii |
| 4-hydroxy-tetrahydrodipicolinate synthase Unclassified |
Ki | 4.05 | - | Escherichia coli |
Adverse Event Associations
DrugCentral / FAERS disproportionality signal rows matched to this compound.
| Reaction PT | Drug AE | LLR | MedDRA |
|---|---|---|---|
| Foetal growth restriction | 15 | 67.493 | 10070531 |
Association rows are source-linked signal records, not incidence rates or clinical causality claims.
IUPHAR Ligand-Target Data
Curated ligand-target interaction rows with action, affinity, and literature identifiers.
| Target | Action | Affinity | PubMed |
|---|---|---|---|
| GluN1 GRIN1 |
Agonist | - | - |
| GluN2A GRIN2A |
Agonist | - | - |
| GluN2B GRIN2B |
Agonist | - | - |
| GluN2C GRIN2C |
Agonist | - | - |
| GluN2D GRIN2D |
Agonist | - | - |
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| Aspartic Acid | 1169 | SU | MTHSPL |
| ASPARTIC ACID | 1169 | SU | MTHSPL |
| aspartic acid | 1169 | SU | MTHSPL |
| aspartic acid | 1169 | IN | RXNORM |
| L-aspartic acid | 1169 | SY | RXNORM |
| aspartate | 42543 | IN | RXNORM |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Aspartic Acid used for in pharmaceutical contexts?
Aspartic Acid (CAS 56-84-8) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Aspartic Acid?
Aspartic Acid has 2 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Foetal growth restriction, Blood calcium increased. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Aspartic Acid also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for L-Aspartic Acid with EU status "permitted".
What clinical phase is Aspartic Acid in?
Aspartic Acid is rendered with ChEMBL max phase 3.
What bioactivity targets are documented for Aspartic Acid?
Aspartic Acid has 23 bioactivity rows in this page query. Rendered target entries include Calcium-binding mitochondrial carrier protein Aralar1, Aspartate aminotransferase, cytoplasmic, Aspartoacylase, Asparagine synthetase [glutamine-hydrolyzing], Argininosuccinate synthase.