Phloretin
CAS 60-82-2
Phloretin (CAS 60-82-2) is a pharmaceutical compound with 8 bioactivity targets and 0 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | Potency | 22240.160194174758 nM | 68 | - |
| - | MIC | 269.16194444444443 ug.mL-1 | 36 | - |
| - | IC50 | 24198.478181818184 nM | 22 | - |
| - | MIC | 55111.11111111111 nM | 9 | - |
| - | AC50 | 17732.432 nM | 5 | - |
| - | IC50 | 27.92 ug.mL-1 | 2 | - |
| - | Ki | 59140 nM | 2 | - |
| - | Kd | 8100 nM | 1 | - |
IUPHAR Ligand-Target Data
Curated ligand-target interaction rows with action, affinity, and literature identifiers.
| Target | Action | Affinity | PubMed |
|---|---|---|---|
| AQP9 AQP9 |
Inhibitor | - | - |
| ClC-3 CLCN3 |
Channel blocker | 4.5 pIC50 | - |
| Sodium-dependent vitamin C transporter 1 SLC23A1 |
Inhibition | 4.190000057220459 pKi | 10331392 |
| TAS2R14 TAS2R14 |
Agonist | 4.519999980926514 pEC50 | 24117141 |
| TAS2R39 TAS2R39 |
Agonist | 4.380000114440918 pEC50 | 24117141 |
| solute carrier family 60 member 2 Mfsd4b4 |
Inhibition | - | 12590146 |
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| PHLORETIN | 1368167 | SU | MTHSPL |
| phloretin | 1368167 | IN | RXNORM |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Phloretin used for in pharmaceutical contexts?
Phloretin (CAS 60-82-2) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Phloretin?
No adverse-event association or SIDER side-effect rows are rendered for Phloretin in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Phloretin also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Phloretin Ingredient Analysis with EU status "permitted".
What clinical phase is Phloretin in?
No phase 1-4 clinical development badge is rendered for Phloretin because the matched compound identifier rows do not contain a max-phase value.