Therapeutic flag Cosmetic cross-reference

Methionine

CAS 63-68-3

Methionine (CAS 63-68-3) is a Phase 3 pharmaceutical compound with 1 bioactivity target and 104 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
4
SOURCE DrugCentral
Adverse signals
104
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Methionine
CAS Number
63-68-3
UNII
AE28F7PNPL
InChIKey
FFEARJCKVFRZRR-BYPYZUCNSA-N
ChEMBL ID
CHEMBL42336
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
Synonyms and normalized names
L-methionine
natural producttherapeutic flag
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 3
Late-stage clinical development phase from the compound identifier source.
ChEMBL CHEMBL42336 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

SOURCE EMBL-EBI ChEMBL 4 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- AC50 30000 nM 28 -
- IC50 60000 nM 1 -
- Ki 61000 nM 1 -
S-ribosylhomocysteine lyase
Unclassified
Ki 4.21 - Bacillus subtilis (strain 168)
SOURCE DrugCentral 11 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PTDrug AE LLRMedDRA
Foetal growth restriction 15 53.771 10070531
Device related sepsis 11 44.044 10069802
Electrolyte imbalance 15 41.94 10014418
Infantile apnoea 8 38.468 10077321
Paraplegia 9 36.119 10033892
Gaze palsy 8 35.665 10056696
Quadriplegia 8 34.669 10037714
Selective eating disorder 8 33.818 10078069
Faecaloma 10 33.179 10056325
Paresis 8 32.882 10033985
General physical health deterioration 26 30.924 10049438

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 5 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
Methionine 6837 SU MTHSPL
METHIONINE 6837 SU MTHSPL
methionine 6837 SU MTHSPL
methionine 6837 IN RXNORM
L-methionine 6837 SY RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Methionine used for in pharmaceutical contexts?

Methionine (CAS 63-68-3) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Methionine?

Methionine has 104 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Foetal growth restriction, Device related sepsis, Electrolyte imbalance, Infantile apnoea, Paraplegia. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Methionine also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for L-Methionine with EU status "permitted".

What clinical phase is Methionine in?

Methionine is rendered with ChEMBL max phase 3.

What bioactivity targets are documented for Methionine?

Methionine has 4 bioactivity rows in this page query. Rendered target entries include S-ribosylhomocysteine lyase.