SCCS/1446/11 18 NOAEL rows Safety conclusion

s are covered by this entry, with the, Parabens; propyl- and butylparaben

Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1446/11.

Opinion Number
SCCS/1446/11
NOAEL Rows
18
Substances Covered
2

Substance(s) Covered

s are covered by this entry, with the Parabens; propyl- and butylparaben

NOAEL Values Extracted from This Opinion

Substance Endpoint Value Study Source
s are covered by this entry, with the NOAEL 2 mg/kg bw/day rat
Regulatory source
p.8
SCCS Opinion
s are covered by this entry, with the NOAEL 1 reproductive toxicity
human
dermal
SCCS Opinion
p.8
SCCS Opinion
s are covered by this entry, with the NOAEL 1 reproductive toxicity
human
dermal
SCCS Opinion
p.8
SCCS Opinion
s are covered by this entry, with the NOAEL 1 reproductive toxicity
human
dermal
SCCS Opinion
p.8
SCCS Opinion
s are covered by this entry, with the NOAEL 2 mg/kg bw/day dermal absorption
rat
dermal
17 days
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the NOAEL 2 mg/kg bw/day dermal absorption
rat
dermal
17 days
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the NOAEL 2 mg/kg bw/day dermal absorption
rat
dermal
17 days
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the NOAEL 3.7 % dermal absorption
dermal
SCCS Opinion
p.12
SCCS Opinion
s are covered by this entry, with the NOAEL 3.7 % dermal absorption
dermal
SCCS Opinion
p.12
SCCS Opinion
s are covered by this entry, with the NOAEL 3.7 % dermal absorption
dermal
SCCS Opinion
p.12
SCCS Opinion
s are covered by this entry, with the NOAEL 17 reproductive toxicity
rat
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the NOAEL 17 reproductive toxicity
rat
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the NOAEL 17 reproductive toxicity
rat
SCCS Opinion
p.6
SCCS Opinion
s are covered by this entry, with the dermal absorption 2 mg/kg bw/day dermal absorption
rat
dermal
17 days
Regulatory source
p.6
SCCS Opinion
s are covered by this entry, with the dermal absorption 2 mg/kg bw/day dermal absorption
rat
dermal
Regulatory source
p.8
SCCS Opinion
s are covered by this entry, with the dermal absorption 3.7 % dermal absorption
dermal
Regulatory source
p.12
SCCS Opinion
s are covered by this entry, with the reproductive toxicity 1 reproductive toxicity
human
dermal
Regulatory source
p.8
SCCS Opinion
s are covered by this entry, with the reproductive toxicity 17 reproductive toxicity
rat
Regulatory source
p.6
SCCS Opinion

Safety Conclusion

sccs_opinions Max 0.25%
safe

Key concerns: sensitisation potential cannot be excluded

Opinion date: 20 September 2011

Source Citation

Primary source https://health.ec.europa.eu/scientific-committees/scientific-committee-consumer-safety-sccs/sccs-opinions_en