SCCS/1651/23
75 NOAEL rows
codes ............................................... 10
Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1651/23.
Opinion Number
SCCS/1651/23
NOAEL Rows
75
Substances Covered
1
Substance(s) Covered
codes ............................................... 10
NOAEL Values Extracted from This Opinion
| Substance | Endpoint | Value | Study | Source |
|---|---|---|---|---|
|
codes ............................................... 10
94-26-8
|
NOAEL | 2 % |
rat oral 12 weeks |
Regulatory source
p.36
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 2 mg/kg bw/day | rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 2 mg/kg bw/day |
rat 17 days |
Regulatory source
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 2 mg/ kg bw /day | rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 2 mg/kg bw/day | rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 10 mg/kg bw/day | Not recorded |
Regulatory source
p.99
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 10 mg/kg bw/day | Not recorded |
Regulatory source
p.105
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 10 mg/kg bw |
mouse 7 days |
Regulatory source
p.103
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 26.9 mg/kg |
mouse 7 days |
Regulatory source
p.103
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 26.9 mg/kg | mouse |
Regulatory source
p.103
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 93 | rat |
Regulatory source
p.93
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 100 mg/kg bw/day | rat |
Regulatory source
p.91
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 100 mg/kg bw/ day |
rat 3 days |
Regulatory source
p.91
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 150 mg/kg bw/day |
rat 57 days |
Regulatory source
p.103
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 310 mg/kg | mouse |
Regulatory source
p.103
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 325 mg/kg bw/day | rat |
Regulatory source
p.37
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 400 mg/kg bw/day |
rat oral 10 weeks |
Regulatory source
p.91
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 400 mg/kg bw/day |
rat 3 days |
Regulatory source
p.91
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 900 mg/kg bw/day |
mouse oral 30 days |
Regulatory source
p.36
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 900 mg/kg bw/day |
mouse oral 12 weeks |
Regulatory source
p.37
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 940 mg/kg bw/day |
rat 78 weeks |
Regulatory source
p.37
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 949 mg/kg/day | mouse |
Regulatory source
p.93
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 949 mg/kg bw/day | mouse |
Regulatory source
p.39
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 949 mg/kg/day | mouse |
Regulatory source
p.93
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 950 mg/kg bw/day | Not recorded |
Regulatory source
p.93
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 950 mg/kg bw/day | mouse |
Regulatory source
p.93
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 1000 mg/kg bw/day |
rat 3 days |
Regulatory source
p.94
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 1504 mg/kg bw/day | Not recorded |
Regulatory source
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 5000 ppm | Not recorded |
Regulatory source
p.44
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 5000 ppm | Not recorded |
Regulatory source
p.44
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 10000 ppm |
rat oral |
Regulatory source
p.40
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 14.4 mg/kgbw/day |
reproductive toxicity rat oral 21 days |
SCCS Opinion
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 14.4 mg/kgbw/day |
reproductive toxicity rat oral 21 days |
SCCS Opinion
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 14.4 mg/kgbw/day |
reproductive toxicity rat oral 21 days |
SCCS Opinion
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
NOAEL | 14.4 mg/kgbw/day |
reproductive toxicity rat oral 21 days |
SCCS Opinion
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
developmental toxicity | 160 mg/kg bw/day |
developmental toxicity rat developmental |
Regulatory source
p.97
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
developmental toxicity | 1000 mg/kg bw/day |
developmental toxicity rat oral Developmental |
Regulatory source
p.39
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 2 mg/kg bw/day |
repeated dose toxicity mouse oral |
Regulatory source
p.35
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 2 mg/kg bw/day |
repeated dose toxicity mouse oral |
Regulatory source
p.35
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 2 mg/kg bw/day |
repeated dose toxicity oral subchronic |
Regulatory source
p.35
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 2 mg/kg bw/day |
repeated dose toxicity oral subchronic |
Regulatory source
p.35
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | ~40 % |
repeated dose toxicity rat oral 8week |
Regulatory source
p.94
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 50 mg/kg |
repeated dose toxicity rat oral 8 weeks |
Regulatory source
p.101
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 67.8 mg/kg bw/day |
repeated dose toxicity rat oral 8 weeks |
Regulatory source
p.101
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 250 mg/kg bw/day |
repeated dose toxicity rat oral 3 days |
Regulatory source
p.94
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 325 mg/kgbw/d |
repeated dose toxicity human developmental |
Regulatory source
p.64
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 325 mg/kg bw/d |
repeated dose toxicity human developmental |
Regulatory source
p.64
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 1086.6 mg/kg bw/day |
repeated dose toxicity rat oral 8 weeks |
Regulatory source
p.101
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
repeated dose toxicity | 1086.6 mg/kg bw/day |
repeated dose toxicity rat oral 8 weeks |
Regulatory source
p.101
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 2 mg/kg bw/day |
reproductive toxicity rat 17 days |
Regulatory source
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 2 mg/kg bw/day |
reproductive toxicity rat oral |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 2 mg/kg bw/day |
reproductive toxicity mouse oral |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 2 mg/kg bw/day |
reproductive toxicity mouse oral developmental |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 2 mg/kg bw/day |
reproductive toxicity mouse oral developmental |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 5 |
reproductive toxicity developmental |
Regulatory source
p.38
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 10.4 mg/kg bw/day |
reproductive toxicity rat oral 21 days |
Regulatory source
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 14.4 mg/kgbw/day |
reproductive toxicity rat oral 21 days |
Regulatory source
p.41
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 100 mg/kg bw/day |
reproductive toxicity rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 100 mg/kg bw/day |
reproductive toxicity rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 160 mg/kg bw/day |
reproductive toxicity rat oral |
Regulatory source
p.98
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 200 mg/ kg bw/day |
reproductive toxicity rat |
Regulatory source
p.96
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 325 mg/kg bw/day |
reproductive toxicity rat developmental |
Regulatory source
p.38
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 325 mg/kg/day |
reproductive toxicity developmental |
Regulatory source
p.45
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 325 mg/kg bw/d |
reproductive toxicity developmental |
Regulatory source
p.45
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 325 mg/kg bw/d |
reproductive toxicity developmental |
Regulatory source
p.45
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 900 mg/kg bw/day |
reproductive toxicity rat developmental |
Regulatory source
p.38
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 1000 mg/kg bw/day |
reproductive toxicity rat oral Developmental |
Regulatory source
p.39
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 1000 mg/kg/day |
reproductive toxicity rat 15-day |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 1000 mg/kg/day |
reproductive toxicity rat 15-day |
Regulatory source
p.42
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 1000 mg/kg bw/day |
reproductive toxicity developmental |
Regulatory source
p.43
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 1504 mg/kg bw/day |
reproductive toxicity mouse oral 27 days |
Regulatory source
p.40
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 5000 ppm |
reproductive toxicity rat oral 11 weeks |
Regulatory source
p.38
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 10000 ppm |
reproductive toxicity rat oral |
Regulatory source
p.40
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 10000 ppm |
reproductive toxicity rat oral |
Regulatory source
p.40
SCCS Opinion
|
|
codes ............................................... 10
94-26-8
|
reproductive toxicity | 40000 ppm |
reproductive toxicity rat oral 11 weeks |
Regulatory source
p.39
SCCS Opinion
|
Safety Conclusion
No matching safety conclusion table row was found. Available SCCS data from noael_studies is shown above.